Vayalil founded Burjeel Holdings in 2007. Today, it has 16 hospitals and 23 medical centers, as well as pharmacies and other services in MENA. In August 2022, the group signed an MoU with Saudi’s Ministry of Investment to invest up to $1 billion in the kingdom by 2030. VPS Healthcare Holdings owns 70% of the company, and Abu Dhabi’s IHC acquired a 15% stake in September 2022. In October 2022, Burjeel Holdings was listed on ADX, after raising nearly $300 million in its IPO. Vayalil had a net worth of $2.3 billion in February 2023. He is also a member of the U.A.E. Medical Council and the advisory committee of the University of Sharjah College of Medicine.