University of Pittsburgh ^{Research centres}

The area of interest is understanding the pathways regulating mammalian aging. The current focus involves dissecting the role of mitochondria, metabolism, and autophagy/mitophagy in the aging process.Aging Institute is actively pursuing novel therapeutic approaches including the design and testing of small molecules that might improve health span- the period of time in which individuals are free of debilitating diseases. While a number of complementary approaches are being pursued, a major emphasis of the lab is developing and characterizing novel mouse models that will hopefully lead to insight into how and why we age.