Yuri Deigin is CEO of Youthereum Genetics. His company is developing therapies that focus on OSKM, the four Yamanaka factors known for turning cells back into a pluripotent state. Youthereum Genetics is developing an epigenetic rejuvenation gene therapy of aging, building on a 2006 Nobel prize winning work, in which Shinya Yamanaka has shown that an adult cell can be 'reprogrammed' back to embryonic state by OSKM transcription factors. Later research has shown that cells also undergo considerable rejuvenation in the process of reprogramming.