Cláudia Cavadas is PharmD, Master in Cell Biology, and PhD in Pharmacology (2002), University of Coimbra. Cláudia's team investigate the hypothalamus as an underlying mediator and a target for interventional strategies in counteracting aging and related diseases. In this context the group focuses the research on the following scientific questions and strategies: i) Does caloric restriction (CR) delay aging and age-related diseases through hypothalamus-related mechanisms? ii) Could we delay premature aging of Hutchinson Gilford progeria syndrome (HGPS) rodent models, and normal aging, by targeting the hypothalamus? iii) Hypothalamic changes related to obesity, depression and ageing.