The main areas of interest of Tom Rando's laboratory are muscle stem cell biology (myogenic lineage progression, cell fate determination, asymmetric cell divisions, Notch signaling, Wnt signaling), muscle stem cell aging (epigenetic determinants, local and systemic influences, roles in age-related decline in regeneration and age-related atrophy), muscular dystrophies (disease pathogenesis, biomarkers and non-invasive imaging), tissue engineering (artificial scaffolds, regenerative therapies) and basic muscle cell biology (myogenic differentiation, muscle development). The Rando laboratory is a part of the Glenn Center for the Biology of Aging and the Department of Neurology and Neurological Sciences at Stanford University School of Medicine and the Rehab R&D Center of Excellence at the VA Palo Alto Health Care System. The laboratory is associated with the Stanford Center on Longevity (SCL). Funding for the research comes from the Glenn Foundation for Medical Research , the NIH (NIA, NIAMS, and NINDS), the Department of Veterans Affairs, the Muscular Dystrophy Association, the American Federation for Aging Research and the Duchenne Parent Project (Netherlands).