Vincent Mouly is working on the molecular and cellular actors involved in human muscle regeneration, in muscle ageing and in muscular dystrophies including oculopharyngeal muscular dystrophy (OPMD) and Duchenne muscular dystrophy (DMD). More precisely, the team is working on RNA metabolism, muscle regeneration, muscle aging, muscle stem cells, and fibrosis using cellular models such as cellular senescence with the final aim of developing innovative therapeutic approaches. The research lab have a strong expertise on human cellular models (this includes the immortalization facility that we have initiated) – and xenotransplantation (this includes several immunodeficient mouse models and grafting procedures).