Sheeba Irshad is a CRUK-clinician scientist (KCL) and a Breast Cancer Medical Oncologist at Guy’s & St Thomas’ NHS Trust. Her research group focuses on understanding the tumour-immune cell cross talk in chemotherapy resistant cancers with a specific emphasis on understanding mechanisms that underpin how cells from the immune system move within tumours, with an ultimate goal to develop more effective immunotherapy treatments for patients. She is also the translational lead and coordinating investigator for a clinical trial platform exploring the potential interactions between DNA damage response inhibitors and immunotherapy in high-risk Triple Negative Breast Cancers.