Anthony Grace is a Distinguished Professor of Neuroscience, Professor of Psychiatry and Psychology at the University of Pittsburgh. Grace has been involved in translational research related to the dopamine system for over 30 years. His early work pioneered the mode of action of antipsychotic drugs and the identification and characterization of dopamine-containing neurons, and he was the first to provide a means to quantify their activity state and pattern in a way that is the standard in the literature. His current work involves the role of dopamine in anhedonia and affective disorders, the mode of action of ketamine and novel antidepressant drugs, and novel treatments for schizophrenia and its prevention.