Dr. Shai Efrati, MD specializes in internal medicine and in hyperbaric medicine. He is a senior physician in Assaf-Harofeh Medical Center, and head of the Assaf-Harofeh Medical Center Research Unit. He has many years of research experience. His research has been published in numerous peer-reviewed journals. He is a Co-Founder of Hospitech respiration Ltd. and serves as its Inventor and Medical Director. Dr. Shai Efrati is the director of the Sagol center for hyperbaric medicine and research at Assaf-Harofeh Medical Center in Israel. The center, under Dr. Efrati’s management, has become the largest most occupied hyperbaric center worldwide, currently treating more than 120 patients per day. Dr. Efrati is also the director of Research & Development of Assaf-Harofeh Medical center, affiliated to Tel-Aviv University. Taking the two passions/positions together Dr. Efrati has initiated a research program focusing on the neuroplasticity (regeneration of brain tissue) of Hyperbaric Oxygen Therapy (HBOT). In the first clinical studies, it was proved that HBOT can induce neuroplasticity in post-stroke and Traumatic Brain Injury even years after the acute Insult. The important clinical results gained from the research program have led to fruitful cooperation including a multidisciplinary team focusing on regeneration of injured brain due to early stages of dementia, vascular disease and anoxic brain damage as well as other "aging" tissues.