Jean-Pierre Issa, MD, is the President and Chief Executive Officer of the Coriell Institute for Medical Research, focusing on advancing understanding of human health and disease while providing biomaterials to the scientific community. As an expert in epigenetics, his research has shed light on how gene regulation impacts aging and cancer. His studies revealed the connection between calorie restriction, extended lifespan, and epigenetic changes, and he has explored the potential of epigenetic-based drug discovery for cancer treatment.