University of Leicester: against COVID-19 ^University

EXCEED Study

EXCEED is a study of genes, environment and health.

EXCEED stands for Extended Cohort for E-Health, Environment and DNA. It is an initiative at University of Leicester, Department of Health Sciences, and the research program was re-adapted to address questions about COVID-19
http://www.leicsrespiratorybru.nihr.ac.uk/our-research/our-research-studies/exceed/

This project is partner of the global consortium "The COVID-19 Host Genetics Initiative".
https://www.covid19hg.org/partners/

Research question: contribution to genome-wide association studies of COVID-19 susceptibility and severity
Study design: Longitudinal population study of 10,200 participants with extensive linkage to UK NHS Healthcare records (DNA in all & ~5000 with GWAS data to date, imputed to HRC). Further recruitment from BAME communities to start April 2020. Consent for recruit by genoytpe Cohort profile: https://doi.org/10.1093/ije/dyz073

Research categories: Disease severity; Disease susceptibility

Type: Retrospective(n=500)

Genetic analysis: GWAS

Assays planned: Antibody profiling
Investigators: Martin Tobin